Bittermelon is a climbing shrub cultivated mostly in Asian countries. The plant also grows in tropical areas of Amazon, East Africa, and the Caribbean. Bittermelon fruits are taken as a culinary vegetable in Bangladesh and in the Indian subcontinent. It is also used as a traditional medicinal plant for the treatment of various diseases especially diabetes.

Plant-based medicine has been used cost-effectively worldwide to treat diabetes.  The active principles present in medicinal plants have been reported to possess pancreatic β cells regenerating, insulin-releasing and fighting the problem of insulin resistance.

Ayurveda and other traditional medicinal systems have suggested the use of BitterMelon extract for the treatment of diabetes. Momordica charantia is extracted for its biologically active chemical compounds such as vitamins, minerals, antioxidants, and many other phytochemicals, that is, glycosides, saponins, phenolic constituents, fixed oils, alkaloids, reducing sugars, resins, and free acids main constituents of bitter melon which are responsible for the antidiabetic effects are triterpene, protein, steroid, alkaloid, inorganic, lipid, and phenolic compounds.

Karela extract or Bitter melon extract of herbal powder or herbal extract is also used for the treatment of various other pathological conditions such as dysmenorrhea, eczema, emmenagogue, galactagogue, gout, jaundice, kidney (stone), leprosy, leucorrhea, piles, pneumonia, psoriasis, rheumatism, and scabies. It also possesses abortifacient, anthelmintic, contraceptive, antimalarial, and laxative properties. Recent studies have shown that daily dose Bitter melon extract can also prevent cancer.

Herbochem is one of the largest company of herbal extracts, manufacturer of Bitter melon extract and  they provide both suppliers and exporters from India and USA.

References:

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306384/
2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027280/