Karela extract (BitterMelon) – 15% Bitters

Scientific Name : Mamordica charantia
Common Name : Bitter Melon
Source : Fruit
Composition : Bitters(including charantin) 15%
Applications : Management of diabetes, Promotes menstruation

Bittermelon is a climbing shrub cultivated mostly in Asian countries. The plant also grows in tropical areas of Amazon, East Africa, and the Caribbean. Bittermelon fruits are taken as a culinary vegetable in Bangladesh and in the Indian subcontinent. It is also used as a traditional medicinal plant for the treatment of various diseases especially diabetes.

Plant-based medicine has been used cost-effectively worldwide to treat diabetes.  The active principles present in medicinal plants have been reported to possess pancreatic β cells regenerating, insulin-releasing and fighting the problem of insulin resistance.1

Ayurveda and other traditional medicinal systems have suggested the use of BitterMelon extract for the treatment of diabetes. Momordica charantia is extracted for its biologically active chemical compounds such as vitamins, minerals, antioxidants, and many other phytochemicals, that is, glycosides, saponins, phenolic constituents, fixed oils, alkaloids, reducing sugars, resins, and free acids main constituents of bitter melon which are responsible for the antidiabetic effects are triterpene, protein, steroid, alkaloid, inorganic, lipid, and phenolic compounds.

Karela extract or Bitter melon extract is also used for the treatment of various other pathological conditions such as dysmenorrhea, eczema, emmenagogue, galactagogue, gout, jaundice, kidney (stone), leprosy, leucorrhea, piles, pneumonia, psoriasis, rheumatism, and scabies. It also possesses abortifacient, anthelmintic, contraceptive, antimalarial, and laxative properties. Recent studies have shown that daily dose Bitter melon extract can also prevent cancer. 2

References:

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306384/
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027280/

Technical Specification

Description Dark greenish brown to brown color powder
Loss on drying NMT 5.0% w/w
Loose bulk density 0.25-0.65 g/ml
Tapped bulk density 0.60-1.11 gm/ml
Sieve Test (#40 mesh) NLT 90% w/w through 40 Mesh
 

Bitters by gravimetric (including charantins)

NLT 15.0% w/w
Microbiological profile

  1. Total plate Count
  2. Yeast and Mould
  3. Escherichia coli
  4. Salmonella
  5. Staphylococcus Aureus
  6. Pseudomonas Aeruginosa
  7. Enterobacteriaceae
 N/A

NMT5000 cfu/g

NMT 200 cfu/g

Should be absent/ 10 g

Should be absent/ 10 g

Should be absent/ 10 g

Should be absent/ 10 g

Should be absent/ 10 g

bitter melon
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